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Volume XVII Issue IX

Author Name
Ajit Kumar
Year Of Publication
2025
Volume and Issue
Volume 17 Issue 9
Abstract
Dengue fever is one of the fastest-growing mosquito-borne infectious diseases worldwide, particularly affecting tropical and subtropical regions. Early prediction of dengue outbreaks is essential for effective public health planning and disease prevention. This study proposes a machine learning–based framework to predict dengue outbreaks using climate and environmental variables such as temperature, rainfall, humidity, and wind speed. Historical dengue case data and meteorological information are integrated to train predictive models including Random Forest, Support Vector Machine, and Gradient Boosting algorithms. The dataset is preprocessed using normalization and feature selection to identify key climatic risk factors influencing dengue transmission. Experimental results demonstrate that machine learning models can accurately forecast dengue outbreaks several weeks in advance, achieving high prediction accuracy and improved reliability compared to traditional statistical methods. Th
PaperID
2025/EUSRM/9/2025/617312

Author Name
Kartikeya Mishra, Shalini Singh
Year Of Publication
2025
Volume and Issue
Volume 17 Issue 9
Abstract
संस्कृतभाषा स्वस्य अत्यन्तवैज्ञानिकेन व्याकरणतन्त्रेण जगति विशिष्टं स्थानं धारयति। पाणिनेः अष्टाध्यायी, या सूत्र-वार्तिक-भाष्यरूपेण त्रिस्तरीया वर्तते, आधुनिकसंगणकविज्ञानस्य क्षेत्रे अपि गम्भीरं महत्त्वं प्राप्नोति, यतः तस्याः नियमव्यवस्था, अनुक्रमः, अपवादसिद्धान्तः च संगणकप्रोग्रामभाषायाः रचनातन्त्रेण साम्यं धारयति। एतस्मिन् समीक्षात्मके शोधपत्रे विगत-चत्वारिंशत्-वर्षेभ्यः (1980-तः 2024-पर्यन्तम्) प्रकाशितानां संस्कृतसंगणकीयभाषाविज्ञानविषयकानां प्रमुखकार्याणां समग्रविश्लेषणं प्रस्तूयते। शोधपत्रम् त्रीणि मुख्यक्षेत्राणि आलोचयति— प्रथमं, रूपविज्ञानविश्लेषकाः यथा जेरार्ड-ह्युएट्-महोदयस्य संस्कृतपारम्पर्येण्जिन् [1], अम्बा-कुलकर्णी-महोदयायाः पाणिनि-आधारित-प्रणाली [3], तथा गिरीश-नाथ-झा-महोदयस्य कार्यम् [8]। द्वितीयं, संधिविच्छेदनं तथा पदच्छेदनं, यत्र सांख्यिकीय-प्रतिमानेभ्यः आरभ्य गभीरशिक्षण-आधारित-प्रतिमानान् यावत् विकासः अवलोक्यते [11, 14]। तृतीयं, निर्भरतापार्सनं तथा यन्त्रानुवादः, विशेषतः कारक-सिद्धान्तस्य संगणकीयकार्यान्वयनम् [5, 9]। विश्लेषणेन ज्ञायते यत् प्रारम्भिककार्याणि नियमाधारि
PaperID
2025/EUSRM/9/2025/61734

Author Name
Kalamma, Hina Shahnawaz
Year Of Publication
2025
Volume and Issue
Volume 17 Issue 9
Abstract
Cancer and antimicrobial resistance remain two of the most significant global health challenges, demanding the continuous development of safer and more effective therapeutic agents. Indole has emerged as one of the most valuable heterocyclic scaffolds in medicinal chemistry because of its structural versatility, favourable physicochemical properties, and ability to interact with diverse biological targets. Over the past decade, molecular hybridization strategies have combined the indole nucleus with pharmacologically active heterocycles such as triazoles, oxadiazoles, thiazoles, pyrazoles, benzimidazoles, and quinazolines to produce compounds with enhanced anticancer and antibacterial activities. This review summarizes the medicinal significance of the indole scaffold, major synthetic approaches for indole-based heterocycles, mechanisms underlying their biological activity, recent trends in structure–activity relationship studies, and the role of computational methods in lead optimizat
PaperID
2025/EUSRM/9/2025/61731a